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John Wilkes Booth assassinated President Abraham Lincoln at Ford’s Theatre in Washington, D.C., just five days after Confederate General Robert E. Lee surrendered, effectively ending the Civil War.
James A. Garfield was shot and killed by Charles J. Guiteau, an emotionally disturbed man who wanted a consulship appointment, on July 2, 1881.
President William McKinley was shot by an anarchist at the Pan-American Exposition in Buffalo, New York on September 6, 1901 and died eight days later, becoming the third U.S. president to be assassinated.
John F. Kennedy, the 35th U.S. president, was assassinated on November 22, 1963, in Dallas, Texas, while riding in a presidential motorcade, by Lee Harvey Oswald, and was succeeded by Vice President Lyndon B. Johnson.